Xiaohui Li, PhD, Associate Professor

E-   mail: lixiaohui@gxu.edu.cn

Personal Profile:

202403 - Present: Guangxi University, College of Life Science and Technology, Associate Professor;

20210 - 202403: Guangxi University, College of Life Science and Technology, Postdoctoral Researcher;

201309 - 202012: Huazhong Agricultural University, College of Life Science and Technology, Integrated Master and PhD Program, received a PhD in Science.

Teaching and research results:

He had led several research projects, participated in two key projects and two general projects of the National Natural Science Foundation of China, applied for one national invention patent, and published multiple SCI papers in authoritative journals such as Cell Host & Microbe, mLife, J Biol Chem, and Microbiol Spectr.

Major research projects undertaken under his auspices:

China Postdoctoral Science Foundation, second-level general funding, presided over, completed;

Guangxi University Postdoctoral Research Startup Fund, presided over, completed;

Guangxi University Talent Introduction Startup Fund, presided over, under research.

Research Directions:

Pathogenic Microbiology, focusing on the mechanisms of bacteria and bacteriophage interaction as well as the molecular mechanisms of bacterial adaptation to various environmental stresses.

Mentored students who won awards:

Representative papers and patents:

Xiaohui Li, Xiating Long, Liu Chen, Xiao Guo, Lining Lu, Lihua Hu, and Zheng-Guo He*. Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity. Cell Host & Microbe. 2023, 31(9): 1469-1480.

Xiaohui Li, Liu Chen, Jingjing Liao, Jiechen Hui, Weihui Li, and Zheng-Guo He*. A novel stress-inducible CmtR-ESX3-Zn²⁺ regulatory pathway essential for survival of Mycobacterium bovis under oxidative stress. J Biol Chem. 2020, 295(50): 17083-17099.

Xiaohui Li, Liu Chen, Yuankun Wang, Xiao Guo, and Zheng-Guo He*. Zinc excess impairs Mycobacterium bovis growth through triggering a Zur-IdeR-Iron homeostasis signal pathway. Microbiol Spectr. 2023, 11(5): e0106923.

Liu Chen, Xiaohui Li, Piao Xu, and Zheng-Guo He*. A Novel Zinc Exporter CtpG Enhances Resistance to Zinc Toxicity and Survival in Mycobacterium bovis. Microbiol Spectr. 2022, 10 (2): e0145621.

Yakun Li, Yuyun Wei, Xiao Guo, Xiaohui Li, Lining Lu, Lihua Hu, and Zheng-Guo He*. Insertion sequence transposition activates antimycobacteriophage immunity through an lsr2-silenced lipid metabolism gene island. mLife. 2024, 3(1): 87-100.

何正国, 李肖辉, 陈柳. 一株新型重组 BCG 菌株及其构建方法和应用，发明专利（2023107836352）。